APPLICATIONS · PHARMACEUTICALS & COSMETICS

Controlled vacuum for sensitive production processes.

Mixing, degassing, drying, evaporation, filtration and solvent duties are assessed around product sensitivity, vapour load, contamination boundary and cleaning requirements.

Mixing & degassingLow-temperature dryingSolvent management
Pharmaceutical and cosmetic vacuum processing system
CONTROLLED PROCESS VACUUMProduct + vapour + cleanlinessOne coordinated system
PROCESS ROLE

Support product quality while managing gas and vapour.

The vacuum source sits outside the product-contact boundary but must be selected with that boundary in mind. Product carry-over, solvents, cleaning method and material compatibility influence every upstream protection stage.

01

Vacuum mixing and deaeration

Helps reduce entrained air in creams, gels, liquids and suitable formulations during controlled mixing.

02

Low-temperature drying

Vacuum can support moisture or solvent removal at reduced temperatures where the process permits.

03

Filtration and transfer

Pressure difference and compatible transfer equipment support selected filtration and fluid-handling steps.

04

Vapour and solvent management

Condensation and separation protect the vacuum source and support controlled handling of process vapours.

Cosmetic vacuum mixing and deaeration process
VACUUM DEAERATION

Control mixing, foaming and gas release together.

Viscosity, temperature, batch size, mixing geometry, pressure profile and process time determine the final arrangement.

SELECTING THE RIGHT SYSTEM

Define the process and contamination boundary first.

Four groups of information guide the chamber, protection and vacuum-source selection.

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01

Product and process step

Define formulation, viscosity, temperature and whether the duty is mixing, drying, filtration or distillation.

02

Gas, vapour and solvent load

Provide composition, expected rate, condensability and any hazardous or corrosive characteristics.

03

Cleanability and materials

Set product-contact materials, seal compatibility, cleaning method and permissible contamination.

04

Batch profile and controls

Specify vessel volume, fill level, pressure profile, process time, instrumentation and validation needs.

RELATED SOLUTION FAMILIES

Equipment families for controlled production duties.

Final design depends on product-contact requirements, gas and vapour load, and the required cleaning and control philosophy.

VACUUM MIXING CHAMBERS

VMO Series

Capacity
10–80 L chambers
Pressure / duty
Process-specific
System role
Mixing and deaeration
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LIQUID RING VACUUM PUMPS

ZVT · ZVK

Capacity
280–3700 m³/h
Pressure / duty
33–100 mbar(a)
System role
Wet and solvent-vapour duties
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OIL-SEALED VACUUM PUMPS

ASV Series

Capacity
20–120 m³/h
Pressure / duty
0.5 mbar
System role
Dry and protected vacuum loads
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HYGIENIC DIAPHRAGM PUMPS

Z10–Z30

Capacity
Model-specific
Pressure / duty
Fluid-transfer duty
System role
Compatible process-liquid transfer
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Published family ranges are indicative. Final selection must be checked at the actual operating pressure, gas or material load, temperature, duty cycle and installation conditions.

APPLICATION ENGINEERING

The vacuum source is one part of the complete system.

Reliable performance depends on the pump or blower, protection equipment, line arrangement, controls and the real process operating point.

01

Operating point

Capacity and pressure are checked together at the actual inlet conditions and duty cycle.

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02

Protection equipment

Filters, separators, condensers, receivers and valves are selected around moisture, particles, liquid carry-over and process risk.

Review the Process Load
03

System integration

Pipework, controls, isolation, accessibility and redundancy are included in the final system architecture.

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LET'S REVIEW YOUR APPLICATION

Share the formulation and process requirements.

Provide product properties, batch size, temperature, gas or solvent load, pressure profile, cleaning boundary, materials and control requirements.

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